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Bergamottin

Name: Bergamottin
Brand: TargetMol
SKU: T5S0669
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T5S0669Cas No. 7380-40-7

Alias Bergaptin, Bergamotine, 5-Geranoxypsoralen

1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A^ydiabetic mice.

Bergamottin

🥰Excellent

Purity: 99.99%

Catalog No. T5S0669Alias Bergaptin, Bergamotine, 5-GeranoxypsoralenCas No. 7380-40-7

1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A^ydiabetic mice.

Pack Size	Price	Availability
1 mg	$40	In Stock
5 mg	$89	In Stock
10 mg	$155	In Stock
25 mg	$322	In Stock
50 mg	$478	In Stock
1 mL x 10 mM (in DMSO)	$68	In Stock

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Batch Information

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Purity:99.99%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A^ydiabetic mice.
Targets&IC50	CYP1A2:5.077 μM, CYP2B1:9.495 μM, CYP2B2:4.535 μM, CYP1A1:10.703 nM(Ki), CYP1A1:0.192 μM
Synonyms	Bergaptin, Bergamotine, 5-Geranoxypsoralen

Chemical Properties

Molecular Weight	338.4
Formula	C₂₁H₂₂O₄
Cas No.	7380-40-7
Smiles	CC(C)=CCC\C(C)=C\COc1c2ccoc2cc2oc(=O)ccc12
Relative Density.	1.153g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (192.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9551 mL	14.7754 mL	29.5508 mL	147.7541 mL
5 mM	0.5910 mL	2.9551 mL	5.9102 mL	29.5508 mL
10 mM	0.2955 mL	1.4775 mL	2.9551 mL	14.7754 mL
20 mM	0.1478 mL	0.7388 mL	1.4775 mL	7.3877 mL
50 mM	0.0591 mL	0.2955 mL	0.5910 mL	2.9551 mL
100 mM	0.0296 mL	0.1478 mL	0.2955 mL	1.4775 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc