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Ac-Endothelin-1 (16-21), human acetate

🥰Excellent
Catalog No. T22540L

Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of the ET family, has been shown to discriminate between the two ET receptor subtypes termed ETA and ETB since it activates only the latter ones.

Ac-Endothelin-1 (16-21), human acetate
Other Forms of Ac-Endothelin-1 (16-21), human acetate:
Ac-Endothelin-1 (16-21), humanT22540
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Ac-Endothelin-1 (16-21), human acetate

🥰Excellent
Purity: 99.86%
Catalog No. T22540L
Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of the ET family, has been shown to discriminate between the two ET receptor subtypes termed ETA and ETB since it activates only the latter ones.
Pack SizePriceAvailabilityQuantity
5 mg$29In Stock
10 mg$32In Stock
25 mg$59In Stock
50 mg$88In Stock
100 mg$131In Stock
200 mg$193In Stock
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Purity:99.86%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of the ET family, has been shown to discriminate between the two ET receptor subtypes termed ETA and ETB since it activates only the latter ones.
Chemical Properties
Molecular Weight898.01
FormulaC43H63N9O12
SmilesCCC(C)[C@@H](C(=O)N[C@@H](C(C)CC)C(=O)N[C@@H](CC1=CC2=CC=CC=C2N1)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CN=CN3)NC(=O)C.CC(O)=O
Relative Density.no data available
SequenceAc-His-Leu-Asp-xiIle-xiIle-Ala(indol-2-yl)-OH
Sequence ShortHLDXXX
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (111.36 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1136 mL5.5679 mL11.1357 mL55.6787 mL
5 mM0.2227 mL1.1136 mL2.2271 mL11.1357 mL
10 mM0.1114 mL0.5568 mL1.1136 mL5.5679 mL
20 mM0.0557 mL0.2784 mL0.5568 mL2.7839 mL
50 mM0.0223 mL0.1114 mL0.2227 mL1.1136 mL
100 mM0.0111 mL0.0557 mL0.1114 mL0.5568 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

Ac-Endothelin-1 , human AcetateAcEndothelin1 (1621), human acetateAc Endothelin 1 (16 21), human acetate
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