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Anti-IFNAR1 Antibody (1D959)
😃Good
Catalog No. TMAY-02545
Alias interferon (α, β and ω) receptor 1, interferon (α, β and Ω) receptor 1, interferon (alpha, beta and omega) receptor 1
Anti-IFNAR1 Antibody (1D959) is a Mouse antibody targeting IFNAR1. Anti-IFNAR1 Antibody (1D959) can be used in ELISA(Det).
Anti-IFNAR1 Antibody (1D959)
Anti-IFNAR1 Antibody (1D959)
😃Good
Catalog No. TMAY-02545Alias interferon (α, β and ω) receptor 1, interferon (α, β and Ω) receptor 1, interferon (alpha, beta and omega) receptor 1
Anti-IFNAR1 Antibody (1D959) is a Mouse antibody targeting IFNAR1. Anti-IFNAR1 Antibody (1D959) can be used in ELISA(Det).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA(Det) Reactivity: Human |
| Alias | interferon (α, β and ω) receptor 1, interferon (α, β and Ω) receptor 1, interferon (alpha, beta and omega) receptor 1 |
| Ig Type | Mouse IgG1 |
| Clone | 1D959 |
| Reactivity | Human |
| Application | ELISA(Det) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IFNAR1 (rh IFNAR1; TMPY-02647; P17181-1; Met1-Lys436). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant-negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IFNAR1 Protein (TMPY-02647) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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