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Azetidine-2-carboxylic acid

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Catalog No. T8100Cas No. 2517-04-6

Azetidine-2-carboxylic acid, a non-proteinogenic amino acid homologue of proline found in common [beets], can be misincorporated into proteins in place of proline in various species, including humans, and is both toxic and teratogenic.

Azetidine-2-carboxylic acid

Azetidine-2-carboxylic acid

😃Good
Purity: 98.97%
Catalog No. T8100Cas No. 2517-04-6
Azetidine-2-carboxylic acid, a non-proteinogenic amino acid homologue of proline found in common [beets], can be misincorporated into proteins in place of proline in various species, including humans, and is both toxic and teratogenic.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$29-In Stock
1 mL x 10 mM (in H2O)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.97%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Azetidine-2-carboxylic acid, a non-proteinogenic amino acid homologue of proline found in common [beets], can be misincorporated into proteins in place of proline in various species, including humans, and is both toxic and teratogenic.
Chemical Properties
Molecular Weight101.1
FormulaC4H7NO2
Cas No.2517-04-6
SmilesOC(=O)C1CCN1
Relative Density.1.186g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (494.56 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM9.8912 mL49.4560 mL98.9120 mL494.5598 mL
5 mM1.9782 mL9.8912 mL19.7824 mL98.9120 mL
10 mM0.9891 mL4.9456 mL9.8912 mL49.4560 mL
20 mM0.4946 mL2.4728 mL4.9456 mL24.7280 mL
50 mM0.1978 mL0.9891 mL1.9782 mL9.8912 mL
100 mM0.0989 mL0.4946 mL0.9891 mL4.9456 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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