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Anti-MCM9 Antibody (5A998)
(Synonyms: Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9, MCMDC1DNA helicase MCM9, MCM 9, hMCM9, EC 3.6.4.12, C6orf61) Copy Product Info
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Synonyms: Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9, MCMDC1DNA helicase MCM9, MCM 9, hMCM9, EC 3.6.4.12, C6orf61
Catalog No. TMAH-00742 Copy Product Info
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Anti-MCM9 Antibody (5A998) is a Mouse antibody targeting MCM9. Anti-MCM9 Antibody (5A998) can be used in ELISA,IHC,WB.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-MCM9 Antibody (5A998) is a Mouse antibody targeting MCM9. Anti-MCM9 Antibody (5A998) can be used in ELISA,IHC,WB. |
| Synonyms | Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9, MCMDC1DNA helicase MCM9, MCM 9, hMCM9, EC 3.6.4.12, C6orf61 |
| Ig Type | IgG1 |
| Clone | 5A998 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Purity | >95% |
| Research Background | Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Probably by regulating the localization of the MRN complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. Acts as a helicase in DNA mismatch repair (MMR) following DNA replication errors to unwind the mismatch containing DNA strand. In addition, recruits MLH1, a component of the MMR complex, to chromatin. The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression. Probably by regulating HR, plays a key role during gametogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human DNA helicase MCM9 Protein (1-391AA) |
| Antigen Species | Human |
| Gene Name | MCM9 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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