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Anti-KIR2DL1 Antibody (3O570) (Synonyms: XXbac-BPG184J6.7, XXbac-BCX195L8.1, p58.1, NKAT-1, NKAT1, NKAT, K...)

Name: Anti-KIR2DL1 Antibody (3O570)
Brand: TargetMol
SKU: TMAY-02502
Rating: 4.5 (1 reviews)

Catalog No. TMAY-02502 Copy Product Info

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Anti-KIR2DL1 Antibody (3O570) is a Mouse antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody (3O570) can be used in ELISA.

Anti-KIR2DL1 Antibody (3O570)

Copy Product Info

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Catalog No. TMAY-02502

Synonyms XXbac-BPG184J6.7, XXbac-BCX195L8.1, p58.1, NKAT-1, NKAT1, NKAT, KIR-K64, KIR221, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1, CD158A

Anti-KIR2DL1 Antibody (3O570) is a Mouse antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody (3O570) can be used in ELISA.

Anti-KIR2DL1 Antibody
(3O570)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-KIR2DL1 Antibody (3O570) is a Mouse antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody (3O570) can be used in ELISA.
Synonyms	XXbac-BPG184J6.7, XXbac-BCX195L8.1, p58.1, NKAT-1, NKAT1, NKAT, KIR-K64, KIR221, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1, CD158A
Ig Type	Mouse IgG2b
Clone	3O570
Reactivity	Human
Specificity	Human KIR2DL1
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KIR2DL1 / CD158a (rh KIR2DL1 / CD158a; TMPY-02629; NP_055033.2; Met1-His245). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Killer cell immunoglobulin-like receptor 2DL1 or KIR2DL1 is an inhibitory Natural Killer cell immunoglobulin-like receptor with two extracellular immunoglobulin domains. KIR2DL1 is a member of the Killer cell immunoglobulin-like receptor family whose members are classified by the number of the extracellular immunoglobulin domains and the length of the cytoplasm domain. KIR2DL1 is a transmembrane glycoprotein expressed by natural killer cells and subsets of T cells. KIR2DL1 down-regulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. It has been reported that the KIR2DL1 is bound to its class I MHC ligand, HLA-Cw4. The KIR2DL1-HLA-Cw4 interface exhibits charge and shape complementarity. Specificity is mediated by a pocket in KIR2DL1 that hosts the Lys80 residue of HLA-Cw4. Many residues conserved in HLA-C and KIR2DL receptors make different interactions in KIR2DL1-HLA-Cw4 and a previously reported KIR2DL2-HLA-Cw3 complex. A dimeric aggregate of KIR-HLA-C complexes was observed in one KIR2DL1-HLA-Cw4 crystal.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human KIR2DL1 / CD158a Protein (TMPY-02629)
Antigen Species	Human
Biology Area	ITIM/ITAM Immunoreceptors and Related Molecules

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

NKAT 1KIR-221KIR 221

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