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Anti-DDR1 Antibody (3D10)
😃Good
Catalog No. TMAY-01113
Alias PTK3A, NEP, discoidin domain receptor tyrosine kinase 1, CD167a, Cak, AI323681, 6030432F18
Anti-DDR1 Antibody (3D10) is a Rabbit antibody targeting DDR1. Anti-DDR1 Antibody (3D10) can be used in ELISA(Cap).
Anti-DDR1 Antibody (3D10)
Anti-DDR1 Antibody (3D10)
😃Good
Catalog No. TMAY-01113Alias PTK3A, NEP, discoidin domain receptor tyrosine kinase 1, CD167a, Cak, AI323681, 6030432F18
Anti-DDR1 Antibody (3D10) is a Rabbit antibody targeting DDR1. Anti-DDR1 Antibody (3D10) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-DDR1 Antibody (3D10) is a Rabbit antibody targeting DDR1. Anti-DDR1 Antibody (3D10) can be used in ELISA(Cap). |
| Alias | PTK3A, NEP, discoidin domain receptor tyrosine kinase 1, CD167a, Cak, AI323681, 6030432F18 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3D10 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human DDR1/MCK10/CD167 (rh DDR1/MCK10/CD167; TMPY-01289; NP_001945.3; Met1-Thr416). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracellular domain homologous to Dictyostellium discoideum protein discoidin 1. Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Expression of DDR1/MCK10/CD167 is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. DDR1/MCK10/CD167 plays an important role in regulating attachment to collagen, chemotaxis, proliferation, and MMP production in smooth muscle cells. DDR1 functions in a feedforward loop to increase p53 levels and at least some of its effectors. Inhibition of DDR1 function resulted in strikingly increased apoptosis of wild-type p53-containing cells in response to genotoxic stress through a caspase-dependent pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human DDR1/MCK10/CD167 Protein (TMPY-01289) |
| Antigen Species | Human |
| Biology Area | Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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