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Rizedisben

Name: Rizedisben
Brand: TargetMol
SKU: T81266
Rating: 4.5 (1 reviews)

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Catalog No. T81266Cas No. 1311570-07-6

Alias GE3126

Rizedisben (GE3126) is a fluorophore developed for fluorescence image-guided surgery, significantly reducing non-specific fluorescence in adipose tissue and enhancing nerve visibility [1].

Rizedisben

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Catalog No. T81266Alias GE3126Cas No. 1311570-07-6

Rizedisben (GE3126) is a fluorophore developed for fluorescence image-guided surgery, significantly reducing non-specific fluorescence in adipose tissue and enhancing nerve visibility [1].

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mg	Inquiry	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Rizedisben (GE3126) is a fluorophore developed for fluorescence image-guided surgery, significantly reducing non-specific fluorescence in adipose tissue and enhancing nerve visibility [1].
In vivo	Rizedisben (GE3126) administered intravenously (i.v.) at dosages ranging from 1.6 to 46.6 mg/kg as a single dose caused a dose-dependent increase in the fluorescence emission intensity of the sciatic nerves in mice. At doses exceeding 16.6 mg/kg, the enhancement of nerve fluorescence became more moderate. Additionally, as the concentration of GE3126 increased, signal saturation occurred at a slower rate in adipose tissue, with minimal fluorescence observed in the adjacent muscle tissue [1].
Synonyms	GE3126

Chemical Properties

Molecular Weight	519.66
Formula	C₂₉H₃₃N₃O₄S
Cas No.	1311570-07-6
Smiles	O=S(=O)(C1=CC=C(C=CC2=CC=C(C=CC3=CC=C(N)C=C3)C(OC)=C2)C=C1)N4CCN(CCO)CC4

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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