Powder: -20°C for 3 years | In solvent: -80°C for 1 year
sEH Inhibitor-16, a potent soluble epoxide hydrolase (sEH) inhibitor, exhibits an IC50 of 2 nM. It diminishes inflammatory damage associated with cerulein-induced acute pancreatitis (AP) in mice, making it suitable for inflammation and immunology research [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | sEH Inhibitor-16, a potent soluble epoxide hydrolase (sEH) inhibitor, exhibits an IC50 of 2 nM. It diminishes inflammatory damage associated with cerulein-induced acute pancreatitis (AP) in mice, making it suitable for inflammation and immunology research [1]. |
In vivo | sEH inhibitor-16 (Compound 28) at a dose of 10 mg/kg, administered intraperitoneally, exerts a protective effect against cerulein-induced acute pancreatitis in mice [1]. Additionally, sEH inhibitor-16 (Compound 28) demonstrates a half-life (T 1/2) of 7.6 hours and a peak concentration (C max) of 4.17 ng/mL in CD-1 mice following the same administration route [1]. |
Molecular Weight | 455.63 |
Formula | C30H37N3O |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
sEH inhibitor-16 Metabolism Epoxide Hydrolase inhibitor inhibit