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Antibacterial agent 106

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Catalog No. T61624Cas No. 2459657-11-3

Antibacterial agent 106 (compound 8) is a highly effective orally active antibacterial compound with antibiofilm activity, demonstrating potent antibacterial effects against multi-drug resistant (MDR) Gram-positive pathogens, including the eradication of 99.7% of intracellular methicillin-resistant S. aureus (MRSA) harbored within macrophages [1].

Antibacterial agent 106

Antibacterial agent 106

😃Good
Catalog No. T61624Cas No. 2459657-11-3
Antibacterial agent 106 (compound 8) is a highly effective orally active antibacterial compound with antibiofilm activity, demonstrating potent antibacterial effects against multi-drug resistant (MDR) Gram-positive pathogens, including the eradication of 99.7% of intracellular methicillin-resistant S. aureus (MRSA) harbored within macrophages [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Antibacterial agent 106 (compound 8) is a highly effective orally active antibacterial compound with antibiofilm activity, demonstrating potent antibacterial effects against multi-drug resistant (MDR) Gram-positive pathogens, including the eradication of 99.7% of intracellular methicillin-resistant S. aureus (MRSA) harbored within macrophages [1].
In vivo
Antibacterial agent 106 (compound 8) effectively penetrates gut cells, appearing in plasma within 15 minutes and maintaining an effective concentration for approximately 12 hours [1].
Chemical Properties
Molecular Weight380.51
FormulaC20H24N6S
Cas No.2459657-11-3
SmilesC(=NNC(=N)N)(C)C=1SC(=NC1C)C2=CC=C(C#CCCN3CCC3)C=C2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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