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Anti-FZD1/Frizzled 1 Antibody (4X478)

😃Good
Catalog No. TMAY-03097
Alias Fzd1, FZ-1, Fz1, frizzled class receptor 1, AW227548

Anti-FZD1/Frizzled 1 Antibody (4X478) is a Rabbit antibody targeting FZD1/Frizzled 1. Anti-FZD1/Frizzled 1 Antibody (4X478) can be used in ELISA.

Anti-FZD1/Frizzled 1 Antibody (4X478)

Anti-FZD1/Frizzled 1 Antibody (4X478)

😃Good
Catalog No. TMAY-03097Alias Fzd1, FZ-1, Fz1, frizzled class receptor 1, AW227548
Anti-FZD1/Frizzled 1 Antibody (4X478) is a Rabbit antibody targeting FZD1/Frizzled 1. Anti-FZD1/Frizzled 1 Antibody (4X478) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$2707-10 days
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Product Introduction

Bioactivity
Description
Anti-FZD1/Frizzled 1 Antibody (4X478) is a Rabbit antibody targeting FZD1/Frizzled 1. Anti-FZD1/Frizzled 1 Antibody (4X478) can be used in ELISA.
AliasFzd1, FZ-1, Fz1, frizzled class receptor 1, AW227548
Ig Type
Rabbit IgG
Clone
4X478
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Frizzled-1 / FZD1 (TMPY-01165; NP_067432.2; Met1-His248).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundFrizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol. Frizzled proteins and the genes encoding them have been identified in an array of animals, from sponges to humans. Frizzled proteins play key roles in governing cell polarity, embryonic development, formation of neural synapses, cell proliferation, and many other processes in developing and adult organisms. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse Frizzled-1 / FZD1 protein (TMPY-01165)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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