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LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 5 mg | $71 | In Stock | |
| 10 mg | $119 | In Stock | |
| 25 mg | $223 | In Stock | |
| 50 mg | $333 | In Stock | |
| 100 mg | $470 | In Stock | |
| 200 mg | $662 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $103 | In Stock |
| Description | LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. |
| Targets&IC50 | ULK1:18.94 nM (EC50) |
| In vitro | LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo |
| Synonyms | LYN-1604 2HCl(2216753-86-3 free base) |
| Molecular Weight | 657.54 |
| Formula | C33H45Cl4N3O2 |
| Cas No. | 2310109-38-5 |
| Smiles | Cl.Cl.CC(C)CN(CC(C)C)CC(=O)N1CCN(CC(OCc2ccc3ccccc3c2)c2ccc(Cl)cc2Cl)CC1 |
| Relative Density. | no data available |
| Color | White |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 25 mg/mL (38.02 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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