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Skyrin

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Catalog No. T36072Cas No. 602-06-2
Alias Rhodophyscin, Endothianin

Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines.

Skyrin

Skyrin

😃Good
Catalog No. T36072Alias Rhodophyscin, EndothianinCas No. 602-06-2
Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines.
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1 mg$45835 days
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Product Introduction

Bioactivity
Description
Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines.
In vitro
Methods: Skyrin (0.0001–100 μM) was treated with plasmid DNA. The effects of skyrin on plasmid DNA were investigated using DNA topology. The potential DNA protection against Fe2+-induced DNA breaks was also assessed. Results: Skyrin at all tested concentrations (0.0001–100 μM) showed no DNA damaging properties (Figure 1). The ability of skyrin to protect plasmid DNA increased in a concentration-dependent manner, and strong DNA protection was observed in samples with higher skyrin concentrations (5–100 μM). [2]
SynonymsRhodophyscin, Endothianin
Chemical Properties
Molecular Weight538.46
FormulaC30H18O10
Cas No.602-06-2
SmilesO=C1C2=CC(=CC(O)=C2C(=O)C=3C(O)=CC(O)=C(C13)C=4C(O)=CC(O)=C5C(=O)C6=C(O)C=C(C=C6C(=O)C54)C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: Soluble
Ethanol: Soluble

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