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Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $458 | 35 days |
Description | Skyrin is a natural bis-anthraquinone derivative and receptor-selective glucagon antagonist that inhibits the growth of HeLa, Vero, K562, Raji, Wish, and Calu-1 tumour cell lines. |
In vitro | Methods: Skyrin (0.0001–100 μM) was treated with plasmid DNA. The effects of skyrin on plasmid DNA were investigated using DNA topology. The potential DNA protection against Fe2+-induced DNA breaks was also assessed. Results: Skyrin at all tested concentrations (0.0001–100 μM) showed no DNA damaging properties (Figure 1). The ability of skyrin to protect plasmid DNA increased in a concentration-dependent manner, and strong DNA protection was observed in samples with higher skyrin concentrations (5–100 μM). [2] |
Synonyms | Rhodophyscin, Endothianin |
Molecular Weight | 538.46 |
Formula | C30H18O10 |
Cas No. | 602-06-2 |
Smiles | O=C1C2=CC(=CC(O)=C2C(=O)C=3C(O)=CC(O)=C(C13)C=4C(O)=CC(O)=C5C(=O)C6=C(O)C=C(C=C6C(=O)C54)C)C |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO: Soluble Ethanol: Soluble |
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