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Choline chloride

🥰Excellent
Catalog No. T1039Cas No. 67-48-1
Alias Hepacholine, Biocoline, Biocolina

Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

Choline chloride

Choline chloride

🥰Excellent
Purity: 99.91%
Catalog No. T1039Alias Hepacholine, Biocoline, BiocolinaCas No. 67-48-1
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$33In StockIn Stock
100 mg$47In StockIn Stock
500 mg$56In StockIn Stock
1 g$64In StockIn Stock
5 g$98-In Stock
10 g$123-In Stock
25 g$198-In Stock
1 mL x 10 mM (in DMSO)$50In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.91%
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Product Introduction

Bioactivity
Description
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
In vitro
After oral administration of Choline chloride, clinical symptoms include restlessness, accelerated respiration, reduced activity, convulsions, wrinkled fur, unsteady gait, and respiratory distress. Choline chloride exhibits low acute oral toxicity. Some animals exhibit diarrhea following ingestion of Choline chloride. In one study, the autopsy revealed pulmonary inflammation in 30% of the rats in the high-dose group.
In vivo
In cell culture, a deficiency of choline can lead to apoptosis, also known as programmed cell death.
SynonymsHepacholine, Biocoline, Biocolina
Chemical Properties
Molecular Weight139.63
FormulaC5H14ClNO
Cas No.67-48-1
Smiles[Cl-].C[N+](C)(C)CCO
Relative Density.1.1 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 27 mg/mL (193.37 mM), Sonication is recommended.
H2O: 26 mg/mL (186.21 mM), Sonication is recommended.
DMSO: 50 mg/mL (358.09 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (23.63 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM7.1618 mL35.8089 mL71.6178 mL358.0892 mL
5 mM1.4324 mL7.1618 mL14.3236 mL71.6178 mL
10 mM0.7162 mL3.5809 mL7.1618 mL35.8089 mL
20 mM0.3581 mL1.7904 mL3.5809 mL17.9045 mL
50 mM0.1432 mL0.7162 mL1.4324 mL7.1618 mL
100 mM0.0716 mL0.3581 mL0.7162 mL3.5809 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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