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Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 mg | $33 | In Stock | In Stock | |
| 100 mg | $47 | In Stock | In Stock | |
| 500 mg | $56 | In Stock | In Stock | |
| 1 g | $64 | In Stock | In Stock | |
| 5 g | $98 | - | In Stock | |
| 10 g | $123 | - | In Stock | |
| 25 g | $198 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock | In Stock |
| Description | Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. |
| In vitro | After oral administration of Choline chloride, clinical symptoms include restlessness, accelerated respiration, reduced activity, convulsions, wrinkled fur, unsteady gait, and respiratory distress. Choline chloride exhibits low acute oral toxicity. Some animals exhibit diarrhea following ingestion of Choline chloride. In one study, the autopsy revealed pulmonary inflammation in 30% of the rats in the high-dose group. |
| In vivo | In cell culture, a deficiency of choline can lead to apoptosis, also known as programmed cell death. |
| Synonyms | Hepacholine, Biocoline, Biocolina |
| Molecular Weight | 139.63 |
| Formula | C5H14ClNO |
| Cas No. | 67-48-1 |
| Smiles | [Cl-].C[N+](C)(C)CCO |
| Relative Density. | 1.1 g/cm3. Temperature:20 °C. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 27 mg/mL (193.37 mM), Sonication is recommended. H2O: 26 mg/mL (186.21 mM), Sonication is recommended. DMSO: 50 mg/mL (358.09 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (23.63 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/Ethanol/DMSO
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