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Obacunone

🥰Excellent
Catalog No. T3390Cas No. 751-03-1

Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.

Obacunone

Obacunone

🥰Excellent
Purity: 99.92%
Catalog No. T3390Cas No. 751-03-1
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$40In Stock
10 mg$64In Stock
25 mg$106In Stock
50 mg$155In Stock
100 mg$228In Stock
200 mg$337In Stock
1 mL x 10 mM (in DMSO)$44In Stock
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Purity:99.92%
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Product Introduction

Bioactivity
Description
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.
Targets&IC50
Aromatase:28.4 μM
Chemical Properties
Molecular Weight454.51
FormulaC26H30O7
Cas No.751-03-1
SmilesC[C@@]12CC[C@@H]3[C@@]4(C)C=CC(=O)OC(C)(C)[C@@H]4CC(=O)[C@@]3(C)[C@]11O[C@@H]1C(=O)O[C@H]2c1ccoc1
Relative Density.1.32 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,store under nitrogen,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
DMSO: 82 mg/mL (180.41 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2002 mL11.0009 mL22.0017 mL110.0086 mL
5 mM0.4400 mL2.2002 mL4.4003 mL22.0017 mL
10 mM0.2200 mL1.1001 mL2.2002 mL11.0009 mL
20 mM0.1100 mL0.5500 mL1.1001 mL5.5004 mL
50 mM0.0440 mL0.2200 mL0.4400 mL2.2002 mL
100 mM0.0220 mL0.1100 mL0.2200 mL1.1001 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

p38MAPKp38 MAPKObacunoneInhibitorinhibitAromataseApoptosis
Related Tags: buy Obacunone | purchase Obacunone | Obacunone cost | order Obacunone | Obacunone chemical structure | Obacunone formula | Obacunone molecular weight
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