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RORγ inverse agonist 1

Name: RORγ inverse agonist 1
Brand: TargetMol
SKU: T67943
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T67943Cas No. 529500-72-9

RORγ inverse agonist 1 has anti-inflammatory activity and can be used to treat rheumatism and psoriasis.

RORγ inverse agonist 1

🥰Excellent

Purity: 99.68%

Catalog No. T67943Cas No. 529500-72-9

RORγ inverse agonist 1 has anti-inflammatory activity and can be used to treat rheumatism and psoriasis.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$32	-	In Stock
25 mg	$53	-	In Stock
50 mg	$78	-	In Stock
100 mg	$117	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.68%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description

RORγ inverse agonist 1 has anti-inflammatory activity and can be used to treat rheumatism and psoriasis.

Chemical Properties

Molecular Weight	463.47
Formula	C₂₂H₂₀F₃N₃O₃S
Cas No.	529500-72-9
Smiles	N(S(=O)(=O)C1=CC=C(C)C=C1)(CC(NCC=2C=CN=CC2)=O)C3=CC(C(F)(F)F)=CC=C3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (107.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1576 mL	10.7882 mL	21.5764 mL	107.8818 mL
5 mM	0.4315 mL	2.1576 mL	4.3153 mL	21.5764 mL
10 mM	0.2158 mL	1.0788 mL	2.1576 mL	10.7882 mL
20 mM	0.1079 mL	0.5394 mL	1.0788 mL	5.3941 mL
50 mM	0.0432 mL	0.2158 mL	0.4315 mL	2.1576 mL
100 mM	0.0216 mL	0.1079 mL	0.2158 mL	1.0788 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc