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Casein kinase 1δ-IN-3

Name: Casein kinase 1δ-IN-3
Brand: TargetMol
SKU: T64350
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T64350Cas No. 349438-77-3

Casein kinase 1δ-IN-3 (Compound 23a) is an inhibitor of casein kinase 1 delta (CK1δ) with a pIC50 of 6.5376 M.

Casein kinase 1δ-IN-3

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Purity: 98.94%

Catalog No. T64350Cas No. 349438-77-3

Casein kinase 1δ-IN-3 (Compound 23a) is an inhibitor of casein kinase 1 delta (CK1δ) with a pIC50 of 6.5376 M.

Pack Size	Price	Availability
1 mg	$32	In Stock
5 mg	$67	In Stock
10 mg	$117	In Stock
25 mg	$247	In Stock
50 mg	$392	In Stock
100 mg	$589	In Stock
200 mg	$839	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

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Batch Information

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Purity:98.94%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Casein kinase 1δ-IN-3 (Compound 23a) is an inhibitor of casein kinase 1 delta (CK1δ) with a pIC50 of 6.5376 M.
Targets&IC50	CKIδ:6.5376 M (pIC50)

Chemical Properties

Molecular Weight	312.39
Formula	C₁₇H₁₆N₂O₂S
Cas No.	349438-77-3
Smiles	COc1ccccc1CC(=O)Nc1nc2ccc(C)cc2s1
Relative Density.	1.299 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 56.7 mg/mL (181.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2011 mL	16.0056 mL	32.0113 mL	160.0563 mL
5 mM	0.6402 mL	3.2011 mL	6.4023 mL	32.0113 mL
10 mM	0.3201 mL	1.6006 mL	3.2011 mL	16.0056 mL
20 mM	0.1601 mL	0.8003 mL	1.6006 mL	8.0028 mL
50 mM	0.0640 mL	0.3201 mL	0.6402 mL	3.2011 mL
100 mM	0.0320 mL	0.1601 mL	0.3201 mL	1.6006 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc