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Moracin O

🥰Excellent
Catalog No. TN1951Cas No. 123702-97-6

Moracin O, a natural product isolated from Morus alba Linn., exhibits cytotoxicity towards 3T3-L1, RAW 264.7, and HEP 3B cells, inhibits HIF-1, and demonstrates neuroprotective and anti-inflammatory effects.

Moracin O

Moracin O

🥰Excellent
Catalog No. TN1951Cas No. 123702-97-6
Moracin O, a natural product isolated from Morus alba Linn., exhibits cytotoxicity towards 3T3-L1, RAW 264.7, and HEP 3B cells, inhibits HIF-1, and demonstrates neuroprotective and anti-inflammatory effects.
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1 mg$162In Stock
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Product Introduction

Bioactivity
Description
Moracin O, a natural product isolated from Morus alba Linn., exhibits cytotoxicity towards 3T3-L1, RAW 264.7, and HEP 3B cells, inhibits HIF-1, and demonstrates neuroprotective and anti-inflammatory effects.
In vitro
Moracin O can dose-dependently increase the survival rate of neuroblastoma SH-SY5Y cells against oxygen-glucose deprivation (OGD)-induced cell death, with a half-maximal effective concentration (EC₅₀) of 12.6μM [2].
Moracin O can reduce the generation of reactive oxygen species (ROS) in OGD-induced cell death, with a half-maximal inhibitory concentration (IC₅₀) of 0.3μM [2].
Moracin O can protect nerve cells from oxidative stress damage caused by oxygen-glucose deprivation [2].
Chemical Properties
Molecular Weight326.34
FormulaC19H18O5
Cas No.123702-97-6
Smiles[C@@](C)(C)(O)[C@H]1CC=2C(=CC3=C(C2)C=C(O3)C4=CC(O)=CC(O)=C4)O1
Relative Density.no data available
ColorWhite
AppearanceLyophilized powder
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (245.14 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0643 mL15.3214 mL30.6429 mL153.2144 mL
5 mM0.6129 mL3.0643 mL6.1286 mL30.6429 mL
10 mM0.3064 mL1.5321 mL3.0643 mL15.3214 mL
20 mM0.1532 mL0.7661 mL1.5321 mL7.6607 mL
50 mM0.0613 mL0.3064 mL0.6129 mL3.0643 mL
100 mM0.0306 mL0.1532 mL0.3064 mL1.5321 mL

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Moracin O
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