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Moracin O

Name: Moracin O
Brand: TargetMol
SKU: TN1951
Price: 162 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1951Cas No. 123702-97-6

Moracin O, a natural product isolated from Morus alba Linn., exhibits cytotoxicity towards 3T3-L1, RAW 264.7, and HEP 3B cells, inhibits HIF-1, and demonstrates neuroprotective and anti-inflammatory effects.

Moracin O

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Purity: 99.77%

Catalog No. TN1951Cas No. 123702-97-6

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$162	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.77%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description

In vitro

Moracin O can dose-dependently increase the survival rate of neuroblastoma SH-SY5Y cells against oxygen-glucose deprivation (OGD)-induced cell death, with a half-maximal effective concentration (EC₅₀) of 12.6μM [2].
Moracin O can reduce the generation of reactive oxygen species (ROS) in OGD-induced cell death, with a half-maximal inhibitory concentration (IC₅₀) of 0.3μM [2].
Moracin O can protect nerve cells from oxidative stress damage caused by oxygen-glucose deprivation [2].

Chemical Properties

Molecular Weight	326.34
Formula	C₁₉H₁₈O₅
Cas No.	123702-97-6
Smiles	[C@@](C)(C)(O)[C@H]1CC=2C(=CC3=C(C2)C=C(O3)C4=CC(O)=CC(O)=C4)O1
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (245.14 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0643 mL	15.3214 mL	30.6429 mL	153.2144 mL
5 mM	0.6129 mL	3.0643 mL	6.1286 mL	30.6429 mL
10 mM	0.3064 mL	1.5321 mL	3.0643 mL	15.3214 mL
20 mM	0.1532 mL	0.7661 mL	1.5321 mL	7.6607 mL
50 mM	0.0613 mL	0.3064 mL	0.6129 mL	3.0643 mL
100 mM	0.0306 mL	0.1532 mL	0.3064 mL	1.5321 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc