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Eleutheroside B1

Name: Eleutheroside B1
Brand: TargetMol
SKU: TN2331
Price: 193 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2331Cas No. 16845-16-2

Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.

Eleutheroside B1

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Purity: 99.73%

Catalog No. TN2331Cas No. 16845-16-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$193	In Stock	In Stock
5 mg	$455	In Stock	In Stock
10 mg	$657	In Stock	In Stock
25 mg	$987	In Stock	In Stock
50 mg	$1,360	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$495	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.73%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities.
In vitro	eleutheroside B1 may affect N?glycan biosynthesis, the chemokine signaling pathway, cytokine?cytokine receptor interaction and, in particular, may target the POLR2A to inhibit the production of influenza virus genes.

Chemical Properties

Molecular Weight	384.33
Formula	C₁₇H₂₀O₁₀
Cas No.	16845-16-2
Smiles	COc1cc2ccc(=O)oc2c(OC)c1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.	1.524 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 75 mg/mL (195.14 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6019 mL	13.0097 mL	26.0193 mL	130.0965 mL
5 mM	0.5204 mL	2.6019 mL	5.2039 mL	26.0193 mL
10 mM	0.2602 mL	1.3010 mL	2.6019 mL	13.0097 mL
20 mM	0.1301 mL	0.6505 mL	1.3010 mL	6.5048 mL
50 mM	0.0520 mL	0.2602 mL	0.5204 mL	2.6019 mL
100 mM	0.0260 mL	0.1301 mL	0.2602 mL	1.3010 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc