Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC 50 values of 29 nM and 7 nM, respectively [1]. OXA-01 demonstrates broad anti-tumor activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 78.00 | |
5 mg | 35 days | $ 348.00 | |
10 mg | 35 days | $ 575.00 | |
25 mg | 35 days | $ 1,330.00 |
Description | OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC 50 values of 29 nM and 7 nM, respectively [1]. OXA-01 demonstrates broad anti-tumor activity. |
In vivo | OXA-01 exhibited extensive anti-tumor efficacy across multiple human xenograft models with diverse histologies. Specifically, in GEO and Colo-205 colon xenograft models, OXA-01 achieved 100% tumor growth inhibition (TGI), outperforming rapamycin, which achieved 75% and 53% TGI, respectively [1]. |
Molecular Weight | 409.87 |
Formula | C21H20ClN5O2 |
CAS No. | 936889-68-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
OXA-01 936889-68-8 OXA01 OXA 01 inhibitor inhibit