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Nalidixic acid

Name: Nalidixic acid
Brand: TargetMol
SKU: T0909
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0909Cas No. 389-08-2

Alias NSC-82174

Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.

Nalidixic acid

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Purity: 99.95%

Catalog No. T0909Alias NSC-82174Cas No. 389-08-2

Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.

Pack Size	Price	Availability	Quantity
5 g	$30	In Stock
1 mL x 10 mM (in DMSO)	$32	In Stock

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Batch Information

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Purity:99.95%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
Synonyms	NSC-82174

Chemical Properties

Molecular Weight	232.24
Formula	C₁₂H₁₂N₂O₃
Cas No.	389-08-2
Smiles	CCN1C=C(C(O)=O)C(=O)C2=CC=C(C)N=C12
Relative Density.	1.331 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 5.63 mg/mL (24.22 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3059 mL	21.5295 mL	43.0589 mL	215.2945 mL
5 mM	0.8612 mL	4.3059 mL	8.6118 mL	43.0589 mL
10 mM	0.4306 mL	2.1529 mL	4.3059 mL	21.5295 mL
20 mM	0.2153 mL	1.0765 mL	2.1529 mL	10.7647 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc