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Iridin

Name: Iridin
Brand: TargetMol
SKU: T3820
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3820Cas No. 491-74-7

Alias Lridin

Iridin (Lridin) is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment

Iridin

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Purity: 99.84%

Catalog No. T3820Alias LridinCas No. 491-74-7

Iridin (Lridin) is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$34	In Stock	In Stock
25 mg	$54	In Stock	In Stock
50 mg	$78	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$42	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.84%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Iridin AI Summary

Iridin shows no inhibition of cow milk xanthine oxidase at a concentration of 50 µg/mL. However, it demonstrates significant inhibitory effects on sodium fluorescein uptake in both OATP1B3-transfected CHO cells and OATP1B1-transfected CHO cells. At an equimolar substrate-inhibitor concentration of 10 µM, Iridin exhibits an inhibition of 90.79% in OATP1B3-transfected cells and 114.51% in OATP1B1-transfected cells. These results suggest that Iridin may have bioactivities related to the inhibition of sodium fluorescein uptake mediated by OATP1B3 and OATP1B1..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Iridin (Lridin) is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment
Synonyms	Lridin

Chemical Properties

Molecular Weight	522.46
Formula	C₂₄H₂₆O₁₃
Cas No.	491-74-7
Smiles	COc1cc(cc(O)c1OC)-c1coc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(OC)c(O)c2c1=O
Relative Density.	1.558 g/cm3 at 20℃

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (105.27 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.83 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9140 mL	9.5701 mL	19.1402 mL	95.7011 mL
5 mM	0.3828 mL	1.9140 mL	3.8280 mL	19.1402 mL
10 mM	0.1914 mL	0.9570 mL	1.9140 mL	9.5701 mL
20 mM	0.0957 mL	0.4785 mL	0.9570 mL	4.7851 mL
50 mM	0.0383 mL	0.1914 mL	0.3828 mL	1.9140 mL
100 mM	0.0191 mL	0.0957 mL	0.1914 mL	0.9570 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc