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Anti-GDF-15 Antibody (7H179)

😃Good
Catalog No. TMAY-01351
Alias PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15

Anti-GDF-15 Antibody (7H179) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (7H179) can be used in ELISA(Det).

Anti-GDF-15 Antibody (7H179)

Anti-GDF-15 Antibody (7H179)

😃Good
Catalog No. TMAY-01351Alias PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Anti-GDF-15 Antibody (7H179) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (7H179) can be used in ELISA(Det).
Pack SizePriceAvailabilityQuantity
20 μL$70 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-GDF-15 Antibody (7H179) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (7H179) can be used in ELISA(Det).
AliasPTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Ig Type
Monoclonal Mouse IgG1
Clone
7H179
Reactivity
Human
Application
ELISA(Det)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GDF15/MIC-1 (rh GDF15/MIC-1; TMPY-04727; NP_004855.2; Ala197-Ile308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0
Research BackgroundGrowth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
HRP
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human GDF15/MIC-1 Protein (TMPY-04727)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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