Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AC-099 (compound 3) serves as a selective full agonist at NPFF2R (EC50 = 1189 nM) and a partial agonist at NPFF1R (EC50 = 2370 nM). It has been shown to mitigate hypersensitivity induced by spinal nerve ligation in rats [1] [2].
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Description | AC-099 (compound 3) serves as a selective full agonist at NPFF2R (EC50 = 1189 nM) and a partial agonist at NPFF1R (EC50 = 2370 nM). It has been shown to mitigate hypersensitivity induced by spinal nerve ligation in rats [1] [2]. |
In vivo | Compound AC-099 (化合物 3; 30 mg/kg; i.p.; single dose) completely attenuated the hypersensitivity in rats induced by SNL (脊神经结扎) [2]. |
Molecular Weight | 264.64 |
Formula | C9H8ClF3N4 |
CAS No. | 849459-88-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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AC-099 849459-88-7 inhibitor inhibit