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Batoclimab
(Synonyms: RVT-1401, RVT1401, IMVT-1401, IMVT1401, HBM9161, HBM 9161) Copy Product Info
🥰Excellent
Synonyms: RVT-1401, RVT1401, IMVT-1401, IMVT1401, HBM9161, HBM 9161
Catalog No. T78245 Copy Product Info
Purity: 95%
🥰Excellent
Batoclimab (RVT-1401) is a fully humanized immunoglobulin G1 (IgG1) monoclonal antibody that specifically targets the neonatal Fc receptor (FcRn) with high affinity for the IgG-binding site on FcRn, and by competitively binding to this site, Batoclimab effectively blocks FcRn-mediated recycling of immunoglobulin G (IgG), resulting in the enhanced degradation of IgG and subsequent reductions in circulating IgG levels, making it a candidate compound for research in autoimmune diseases such as myasthenia gravis and thyroid eye disease.
Batoclimab
Cas No. 2187430-05-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $322 | - | In Stock | |
| 5 mg | $790 | - | In Stock | |
| 10 mg | $1,290 | - | In Stock | |
| 25 mg | $1,890 | - | In Stock | |
| 50 mg | $2,570 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.7% (SDS-PAGE); 96.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Batoclimab (RVT-1401) is a fully humanized immunoglobulin G1 (IgG1) monoclonal antibody that specifically targets the neonatal Fc receptor (FcRn) with high affinity for the IgG-binding site on FcRn, and by competitively binding to this site, Batoclimab effectively blocks FcRn-mediated recycling of immunoglobulin G (IgG), resulting in the enhanced degradation of IgG and subsequent reductions in circulating IgG levels, making it a candidate compound for research in autoimmune diseases such as myasthenia gravis and thyroid eye disease. |
| Synonyms | RVT-1401, RVT1401, IMVT-1401, IMVT1401, HBM9161, HBM 9161 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | FcRn (FCGRT & B2M) |
| Molecular Weight | 143.44 kDa |
| Cas No. | 2187430-05-1 |
| Isotype | Human IgG1 lambda2 |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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