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TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 100 mg | Inquiry | Inquiry | Inquiry | |
| 500 mg | Inquiry | Inquiry | Inquiry |
| Description | TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells. |
| Synonyms | FSL 1 |
| Molecular Weight | 1666.16 |
| Formula | C84H140N14O18S |
| Cas No. | 322455-70-9 |
| Smiles | C([C@H](CC1=CN=CN1)NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(CNC([C@H](CSCC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)N)=O)=O)CC(O)=O)=O)CCC2)CCCCN)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CO)=O)CCCCN)=O)CCC3 |
| Relative Density. | no data available |
| Sequence | Ser-(2,3-Bispalmitoyloxypropyl)-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe |
| Sequence Short | S-(2,3-Bispalmitoyloxypropyl)-CGDPKHPKSF |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | H2O: 2 mg/mL (1.2 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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