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L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $2,140 | 10-14 weeks | 10-14 weeks | |
| 50 mg | $2,785 | 10-14 weeks | 10-14 weeks | |
| 100 mg | $3,520 | 10-14 weeks | 10-14 weeks |
| Description | L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1]. |
| In vitro | L-2'-Fd4C (0-10 μM; 9 d; HepG2-2.2.15 cells) inhibits hepatitis B virus (HBV) replication with an EC50 of 0.002 μM [1]. |
| In vivo | L-2'-Fd4C, administered intraperitoneally at a dosage of 100 mg/kg daily for 7 days, demonstrates significant anti-hepadnaviral activity in HBV-transgenic mice, resulting in a reduction of hepatitis B virus (HBV) levels in the blood comparable to the effects of Lamivudine [1]. |
| Molecular Weight | 227.19 |
| Formula | C9H10FN3O3 |
| Cas No. | 221662-50-6 |
| Smiles | FC=1[C@H](O[C@@H](CO)C1)N2C(=O)N=C(N)C=C2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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