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CHK1 inhibitor

Name: CHK1 inhibitor
Brand: TargetMol
SKU: T10793
Rating: 4.5 (1 reviews)

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Catalog No. T10793Cas No. 2097938-64-0

Alias GDC-0575 analog

CHK1 inhibitor (GDC-0575 analog) functions as a CHK1 inhibitor.

CHK1 inhibitor

😃Good

Catalog No. T10793Alias GDC-0575 analogCas No. 2097938-64-0

CHK1 inhibitor (GDC-0575 analog) functions as a CHK1 inhibitor.

Pack Size	Price	Availability
25 mg	$1,670	8-10 weeks
50 mg	$2,180	8-10 weeks
100 mg	$2,800	8-10 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	CHK1 inhibitor (GDC-0575 analog) functions as a CHK1 inhibitor.
Synonyms	GDC-0575 analog

Chemical Properties

Molecular Weight	377.28
Formula	C₁₇H₂₁BrN₄O
Cas No.	2097938-64-0
Relative Density.	1.570 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (397.58 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6506 mL	13.2528 mL	26.5055 mL	132.5276 mL
5 mM	0.5301 mL	2.6506 mL	5.3011 mL	26.5055 mL
10 mM	0.2651 mL	1.3253 mL	2.6506 mL	13.2528 mL
20 mM	0.1325 mL	0.6626 mL	1.3253 mL	6.6264 mL
50 mM	0.0530 mL	0.2651 mL	0.5301 mL	2.6506 mL
100 mM	0.0265 mL	0.1325 mL	0.2651 mL	1.3253 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc