Shopping Cart

Remove All
Your shopping cart is currently empty

DMT1 blocker 1

Name: DMT1 blocker 1
Brand: TargetMol
SKU: T11063
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T11063Cas No. 1354790-56-9

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.

DMT1 blocker 1

🥰Excellent

Purity: 99.73%

Catalog No. T11063Cas No. 1354790-56-9

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.

Pack Size	Price	Availability
1 mg	$98	In Stock
5 mg	$239	In Stock
10 mg	$378	In Stock
25 mg	$653	In Stock
50 mg	$928	In Stock
100 mg	$1,280	In Stock
200 mg	$1,720	In Stock
1 mL x 10 mM (in DMSO)	$223	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.73%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
Targets&IC50	DMT1:0.64 μM

Chemical Properties

Molecular Weight	294.31
Formula	C₁₆H₁₄N₄O₂
Cas No.	1354790-56-9
Smiles	Cc1nn(c(O)c1C(=O)Nc1ccccc1)-c1ccccn1
Relative Density.	1.31 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (339.78 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3978 mL	16.9889 mL	33.9778 mL	169.8889 mL
5 mM	0.6796 mL	3.3978 mL	6.7956 mL	33.9778 mL
10 mM	0.3398 mL	1.6989 mL	3.3978 mL	16.9889 mL
20 mM	0.1699 mL	0.8494 mL	1.6989 mL	8.4944 mL
50 mM	0.0680 mL	0.3398 mL	0.6796 mL	3.3978 mL
100 mM	0.0340 mL	0.1699 mL	0.3398 mL	1.6989 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc