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ZnAF-1F

Name: ZnAF-1F
Brand: TargetMol
SKU: T87676
Rating: 4.5 (1 reviews)

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Catalog No. T87676Cas No. 443302-08-7

ZnAF-1F, with a Kd value of 2.2 nM, serves as a powerful fluorophore and is effective as fluorescent probes for Zn2+ in cellular applications. It exhibits an excitation wavelength (λ excitation) of 489 nm and an emission wavelength (λ emission) of 514 nm [1] [2] [3].

ZnAF-1F

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Catalog No. T87676Cas No. 443302-08-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
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50 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	ZnAF-1F, with a Kd value of 2.2 nM, serves as a powerful fluorophore and is effective as fluorescent probes for Zn2+ in cellular applications. It exhibits an excitation wavelength (λ excitation) of 489 nm and an emission wavelength (λ emission) of 514 nm [1] [2] [3].
In vitro	ZnAF-1F (1 μM) demonstrates a K_on value of 3.5 × 10^6 M^(-1) s^(-1) and a K_off value of 7.7 × 10^(-3) s^(-1) in 100 mM HEPES buffer [1]. ZnAF-1F serves as a zinc sensor in neutral and slightly acidic conditions [2].

Chemical Properties

Molecular Weight	608.59
Formula	C₃₄H₂₆F₂N₄O₅
Cas No.	443302-08-7
Smiles	O=C1OC2(C=3C1=CC(NCCN(CC4=CC=CC=N4)CC5=CC=CC=N5)=CC3)C=6C(OC=7C2=CC(F)=C(O)C7)=CC(O)=C(F)C6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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