Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of TNF-α, IFN-γ, and interleukin (IL)-12, while enhancing the activity of heme oxygenase 1. It is utilized in research related to ulcerative colitis [1] [2].
Pack Size | Availability | Price/USD | Quantity |
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2 mg | 5 days | $ 65.00 |
Description | Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of TNF-α, IFN-γ, and interleukin (IL)-12, while enhancing the activity of heme oxygenase 1. It is utilized in research related to ulcerative colitis [1] [2]. |
In vivo | Delmitide acetate administered orally at doses of 2.5, 5, and 10 mg/kg daily markedly mitigated CPT-11-induced diarrhea, mucosal inflammation, and mortality in mice by inhibiting the excessive synthesis of proinflammatory cytokines, including TNF-a, IFN-y, and IL-12, in vivo [2]. Furthermore, it fostered an improved tumor response and extended the duration until relapse, all without concurrent gastrointestinal toxicity in the mice [2]. |
Synonyms | RDP-58 acetate |
Molecular Weight | 1288.62 |
Formula | C61H109N17O13 |
CAS No. | 501019-16-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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