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Anti-CD63 Antibody (2H536)

(Synonyms: Tspan30, OMA81H, MLA1, ME491, LAMP-3, CD63 molecule) Copy Product Info
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Synonyms: Tspan30, OMA81H, MLA1, ME491, LAMP-3, CD63 molecule

Catalog No. TMAH-00216 Copy Product Info
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Anti-CD63 Antibody (2H536) is an antibody targeting CD63. Anti-CD63 Antibody (2H536) can be used in ELISA,IF,IHC.
Anti-CD63 Antibody
(2H536)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD63 Antibody (2H536) is an antibody targeting CD63. Anti-CD63 Antibody (2H536) can be used in ELISA,IF,IHC.
SynonymsTspan30, OMA81H, MLA1, ME491, LAMP-3, CD63 molecule
Ig Type
Rabbit IgG
Clone
2H536
Reactivity
Human
Application
Recommended Dose
IHC:1:50-1:200; IF:1:20-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body. Melanosome. Secreted, extracellular exosome. Cell surface.
Tissue SpecificityDetected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundFunctions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human CD63
Antigen Species
Human
Gene Name
CD63
Gene ID
Uniprot ID
Biology Area
Cardiovascular
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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