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Sec-O-Glucosylhamaudol

🥰Excellent
Catalog No. T5S0581Cas No. 80681-44-3
Alias Hamaudol 3-glucoside

Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal Sec-O-Glucosylhamaudol has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor.

Sec-O-Glucosylhamaudol

Sec-O-Glucosylhamaudol

🥰Excellent
Purity: 99.79%
Catalog No. T5S0581Alias Hamaudol 3-glucosideCas No. 80681-44-3
Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal Sec-O-Glucosylhamaudol has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$37In StockIn Stock
10 mg$54In StockIn Stock
25 mg$90In StockIn Stock
50 mg$128In StockIn Stock
100 mg$189-In Stock
1 mL x 10 mM (in DMSO)$48In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.79%
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COA LCMS HPLC HNMR

Product Introduction

Bioactivity
Description
Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal Sec-O-Glucosylhamaudol has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor.
SynonymsHamaudol 3-glucoside
Chemical Properties
Molecular Weight438.43
FormulaC21H26O10
Cas No.80681-44-3
SmilesCc1cc(=O)c2c(O)c3C[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)Oc3cc2o1
Relative Density.1.553g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (182.47 mM), Sonication is recommended.
Pyridine, Methanol, etc.: Soluble
Ethanol: Soluble
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (7.53 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2809 mL11.4043 mL22.8087 mL114.0433 mL
5 mM0.4562 mL2.2809 mL4.5617 mL22.8087 mL
10 mM0.2281 mL1.1404 mL2.2809 mL11.4043 mL
20 mM0.1140 mL0.5702 mL1.1404 mL5.7022 mL
50 mM0.0456 mL0.2281 mL0.4562 mL2.2809 mL
100 mM0.0228 mL0.1140 mL0.2281 mL1.1404 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Sec-O-GlucosylhamaudolSecOGlucosylhamaudolSec O GlucosylhamaudolOpioidReceptorOpioid ReceptorInhibitorinhibit
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