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Anti-IFNLR1 Antibody (9X278)
😃Good
Catalog No. TMAH-00597
Anti-IFNLR1 Antibody (9X278) is a Mouse antibody targeting IFNLR1. Anti-IFNLR1 Antibody (9X278) can be used in ELISA, IF.
Anti-IFNLR1 Antibody (9X278)
Anti-IFNLR1 Antibody (9X278)
😃Good
Catalog No. TMAH-00597
Anti-IFNLR1 Antibody (9X278) is a Mouse antibody targeting IFNLR1. Anti-IFNLR1 Antibody (9X278) can be used in ELISA, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA, IF Reactivity: Human |
| Ig Type | IgG2a |
| Clone | 9X278 |
| Reactivity | Human |
| Verified Activity | 1. Immunofluorescence staining of Hela cells with（TMAH-00597）at 1:90, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). 2. Immunofluorescence staining of U251 cells with（TMAH-00597）at 1:90, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). |
| Application | ELISA, IF |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Purity | >95% |
| Research Background | The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: IFNLR1 Protein (21-228AA) |
| Antigen Species | Human |
| Gene ID | 163702 |
| Uniprot ID | |
| Biology Area | Signal Transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Likely interleukin or cytokine receptor 2 (LICR2)LICR2LICR 2Interleukin-28 receptor subunit α (IL-28 receptor subunit α;IL-28R-α;IL-28RA)Interleukin-28 receptor subunit alpha (IL-28 receptor subunit alpha;IL-28R-alpha;IL-28RA)Interleukin-28 receptor subunit a (IL-28 receptor subunit a;IL-28R-a;IL-28RA)Interferon λ receptor 1Interferon lambda receptor 1IL-28RAIL28RAIFN-λ-R1IFN-λ receptor 1IFN-λ R1IFNλ R1IFNLR1IFNLR 1IFN-lambda-R1IFN-lambda receptor 1IFN-lambda R1Cytokine receptor family 2 member 12 (CRF2-12)Cytokine receptor class-II member 12CRF2-12CRF212
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