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Anti-TIE2 Antibody (1E654) (Synonyms: Tie-2, Tie2, TEK tyrosine kinase, endothelial, STK1, Hyk, Cd202b, AA...)

Catalog No. TMAY-01087 Copy Product Info
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Anti-TIE2 Antibody (1E654) is a Mouse antibody targeting TIE2. Anti-TIE2 Antibody (1E654) can be used in FCM.

Anti-TIE2 Antibody (1E654)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01087
Synonyms Tie-2, Tie2, TEK tyrosine kinase, endothelial, STK1, Hyk, Cd202b, AA517024

Anti-TIE2 Antibody (1E654) is a Mouse antibody targeting TIE2. Anti-TIE2 Antibody (1E654) can be used in FCM.

Anti-TIE2 Antibody
(1E654)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TIE2 Antibody (1E654) is a Mouse antibody targeting TIE2. Anti-TIE2 Antibody (1E654) can be used in FCM.
SynonymsTie-2, Tie2, TEK tyrosine kinase, endothelial, STK1, Hyk, Cd202b, AA517024
Ig Type
Mouse IgG1
Clone
1E654
Reactivity
Human
Specificity
Human TIE-2
Verified Activity
Flow cytometric analysis of Human TIE2(CD202b) expression on HUVEC cells. Cells were stained with purified anti-Human TIE2(CD202b), then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
Recommended Dose
FCM: 0.5-2 μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human TIE2 Protein (TMPY-01064)
Antigen Species
Human
Biology Area
Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets, Hemangioblast Markers
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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