Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM. It demonstrates favorable pharmacokinetic properties in mice, achieving high in vivo exposure and oral bioavailability at low doses [1].
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Description | ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM. It demonstrates favorable pharmacokinetic properties in mice, achieving high in vivo exposure and oral bioavailability at low doses [1]. |
Molecular Weight | 381.4 |
Formula | C20H20FN5O2 |
CAS No. | 2643334-76-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ROCK-IN-9 2643334-76-1 Cell Cycle/Checkpoint Cytoskeletal Signaling Stem Cells ROCK inhibitor inhibit