Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 51.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 163.00 | |
50 mg | In stock | $ 259.00 | |
100 mg | In stock | $ 388.00 | |
200 mg | In stock | $ 583.00 | |
500 mg | In stock | $ 875.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 57.00 |
Description | AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM). |
Targets&IC50 | Dopamine uptake:71 nM |
In vivo | In adult male Sprague Dawley rats, AHN 1-055 hydrochloride (5 mg/kg; i.v.) inhibited the uptaking of brain dopamine with an IC50 of 311.8 ng/ml. The Cmax and T1/2 are 1.48 mg/L and 7.69 h due to 1.8L/h/kg plasma clearance combined with 18.7 L/kg volumes of distribution[1]. |
Synonyms | 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride |
Molecular Weight | 379.87 |
Formula | C21H24ClF2NO |
CAS No. | 202646-03-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 33.33 mg/mL (87.74 mM), Sonication is recommended.
DMSO: 125 mg/mL (329.06 mM)
You can also refer to dose conversion for different animals. More
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AHN 1-055 hydrochloride 202646-03-5 GPCR/G Protein Neuroscience Dopamine Receptor AHN 1 055 hydrochloride transporter Dopamine DAT Dopamine Transporter Inhibitor AHN 1-055 Hydrochloride AHN 1055 hydrochloride 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride SLC6A3 uptake AHN 1-055 inhibit inhibitor