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Anti-VDAC1 Antibody (5H960)
(Synonyms: YNL2441C, YNL055C, Voltage-dependent anion-selective channel protein 1, Voltage dependent anion selective channel protein 1, Voltage dependent anion channel 1, VDAC-1, VDAC, Porin 31HM, Porin 31HL, POR1, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1, OMP2, N2441, Mitochondrial Porin, MGC111064, hVDAC1) Copy Product Info
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Synonyms: YNL2441C, YNL055C, Voltage-dependent anion-selective channel protein 1, Voltage dependent anion selective channel protein 1, Voltage dependent anion channel 1, VDAC-1, VDAC, Porin 31HM, Porin 31HL, POR1, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1, OMP2, N2441, Mitochondrial Porin, MGC111064, hVDAC1
Catalog No. TMAH-01243 Copy Product Info
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Anti-VDAC1 Antibody (5H960) is an antibody targeting VDAC1. Anti-VDAC1 Antibody (5H960) can be used in ELISA,IHC,WB.
Anti-VDAC1 Antibody
(5H960)
(5H960)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-VDAC1 Antibody (5H960) is an antibody targeting VDAC1. Anti-VDAC1 Antibody (5H960) can be used in ELISA,IHC,WB. |
| Synonyms | YNL2441C, YNL055C, Voltage-dependent anion-selective channel protein 1, Voltage dependent anion selective channel protein 1, Voltage dependent anion channel 1, VDAC-1, VDAC, Porin 31HM, Porin 31HL, POR1, Plasmalemmal porin, Outer mitochondrial membrane protein porin 1, OMP2, N2441, Mitochondrial Porin, MGC111064, hVDAC1 |
| Ig Type | Rabbit IgG |
| Clone | 5H960 |
| Reactivity | Human, Mouse, Rat |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Mitochondrion outer membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in erythrocytes (at protein level). Expressed in heart, liver and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Binds various signaling molecules, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol. In depolarized mitochondria, acts downstream of PRKN and PINK1 to promote mitophagy or prevent apoptosis; polyubiquitination by PRKN promotes mitophagy, while monoubiquitination by PRKN decreases mitochondrial calcium influx which ultimately inhibits apoptosis. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. May mediate ATP export from cells. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human VDAC1 |
| Antigen Species | Human |
| Gene Name | VDAC1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Tags & Cell Markers |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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