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Anti-MUC1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-Biotin can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
| Description | Anti-MUC1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-Biotin can be used in ELISA,FCM. |
| Synonyms | Tumor-associated mucin, Tumor-associated epithelial membrane antigen, Polymorphic epithelial mucin, PEMT, Peanut-reactive urinary mucin, Mucin-1, Krebs von den Lungen-6, H23AG, Episialin, Carcinoma-associated mucin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of MUC1 overexpressed 395F cells with TMAZ-0113B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MUC1 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack|The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | MUC1 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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