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Anti-TXN Antibody (3R156) is a Rabbit antibody targeting TXN. Anti-TXN Antibody (3R156) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
| Description | Anti-TXN Antibody (3R156) is a Rabbit antibody targeting TXN. Anti-TXN Antibody (3R156) can be used in ELISA. |
| Synonyms | TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF |
| Ig Type | Rabbit IgG |
| Clone | 3R156 |
| Reactivity | Mouse |
| Specificity | Mouse Thioredoxin/TRX |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Thioredoxin/TXN/SASP (rM Thioredoxin/TXN/SASP; TMPY-00382; P10639; Met1-Val105). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin / TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Thioredoxin / TXN nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Thioredoxin / TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse Thioredoxin/TXN/SASP Protein (TMPY-00382) |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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