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Belrestotug
(Synonyms: GSK4428859A, EOS884448, EOS-448) Copy Product Info
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Synonyms: GSK4428859A, EOS884448, EOS-448
Catalog No. T82901 Copy Product Info
🥰Excellent
Belrestotug (EOS-448), an antagonistic anti-TIGIT (VSIG9, VSTM3) fully human antibody, exhibits antineoplastic activity. Belrestotug is relevant for immuno-oncology investigations involving TIGIT-mediated immune checkpoint regulation, tumor immune microenvironment interactions, and T-cell functional modulation.
Belrestotug
Cas No. 2574438-65-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | - | In Stock | |
| 5 mg | $993 | - | In Stock | |
| 10 mg | $1,590 | - | In Stock | |
| 25 mg | $2,950 | - | In Stock | |
| 50 mg | $4,690 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.4% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Belrestotug (EOS-448), an antagonistic anti-TIGIT (VSIG9, VSTM3) fully human antibody, exhibits antineoplastic activity. Belrestotug is relevant for immuno-oncology investigations involving TIGIT-mediated immune checkpoint regulation, tumor immune microenvironment interactions, and T-cell functional modulation. |
| In vivo | Belrestotug (200mg/mouse; i.p.; every three days; 3 times) reduces TIGIT+Tregs in monotherapy and reduces Treg cells in female BALB/c with 5x105 CT26 (ATCC CRL-2638TM) tumor cells[1]. |
| Synonyms | GSK4428859A, EOS884448, EOS-448 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | TIGIT |
| Cas No. | 2574438-65-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature, -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Belrestotug in vivo
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