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Undecanoic gamma-lactone

Name: Undecanoic gamma-lactone
Brand: TargetMol
SKU: TN6744
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN6744Cas No. 104-67-6

Undecanoic gamma-lactone is a natural product.

Undecanoic gamma-lactone

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Catalog No. TN6744Cas No. 104-67-6

Undecanoic gamma-lactone is a natural product.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$30	-	In Stock
1 g	$41	-	In Stock
2 g	$59	-	In Stock
5 g	$98	-	In Stock
10 g	$146	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Resource Download

COA MS HNMR

Product Introduction

Undecanoic gamma-lactone AI Summary

Undecanoic gamma-lactone has multifaceted bioactivities, including inhibitory activity against recombinant human cytochrome P450 1A2 with an IC50 value of 45000.0 nM. It is also a small molecule agonist that targets the antioxidant response element (ARE) signaling pathway, enhancing Nrf2-dependent transcriptional activity with a potency of 12197.2 nM. Additionally, Undecanoic gamma-lactone functions as an antagonist at human OR5K1 expressed in HEK293 cells, showing over 50% inhibition of a 2,6-dimethylpyrazine-induced response at 100 uM in a luciferase reporter gene assay. This compound also exhibits agonist activity at TRPA1 with an activity level of 27.0% relative to AITC at a concentration of 1000 uM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Undecanoic gamma-lactone is a natural product.

Chemical Properties

Molecular Weight	184.28
Formula	C₁₁H₂₀O₂
Cas No.	104-67-6
Smiles	CCCCCCCC1CCC(=O)O1
Relative Density.	0.9425

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (325.59 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (13.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4265 mL	27.1326 mL	54.2652 mL	271.3262 mL
5 mM	1.0853 mL	5.4265 mL	10.8530 mL	54.2652 mL
10 mM	0.5427 mL	2.7133 mL	5.4265 mL	27.1326 mL
20 mM	0.2713 mL	1.3566 mL	2.7133 mL	13.5663 mL
50 mM	0.1085 mL	0.5427 mL	1.0853 mL	5.4265 mL
100 mM	0.0543 mL	0.2713 mL	0.5427 mL	2.7133 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc