Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TrxR-IN-3 (Compound 2c) is a effective TrxR inhibitor. TrxR-IN-3 shows strong antiproliferative activities against five human cancer cell lines, especially against breast tumor cells. TrxR-IN-3 increases ROS levels and leads to significant apoptosis by regulating the expression of apoptosis-related proteins in the breast cancer cells. TrxR-IN-3 also triggers the formation of autophagosomes and autolysosomes by promoting the expression of LC3-II and Beclin-1 and reducing the expression of LC3-I and p62 proteins [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | TrxR-IN-3 (Compound 2c) is a effective TrxR inhibitor. TrxR-IN-3 shows strong antiproliferative activities against five human cancer cell lines, especially against breast tumor cells. TrxR-IN-3 increases ROS levels and leads to significant apoptosis by regulating the expression of apoptosis-related proteins in the breast cancer cells. TrxR-IN-3 also triggers the formation of autophagosomes and autolysosomes by promoting the expression of LC3-II and Beclin-1 and reducing the expression of LC3-I and p62 proteins [1]. |
Molecular Weight | 268.23 |
Formula | C14H11F3O2 |
CAS No. | 2445565-58-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TrxR-IN-3 2445565-58-0 inhibitor inhibit