Shopping Cart

Your shopping cart is currently empty

N-deacetylated BMS-202

Name: N-deacetylated BMS-202
Brand: TargetMol
SKU: T12143
Price: 62 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T12143Cas No. 2310135-18-1

N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interactions and has potential anticancer activity for cancer research.

N-deacetylated BMS-202

😃Good

Purity: 98.13%

Catalog No. T12143Cas No. 2310135-18-1

N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interactions and has potential anticancer activity for cancer research.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$62	-	In Stock
5 mg	$130	5 days	5 days
1 mL x 10 mM (in DMSO)	$128	5 days	5 days

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.13%

Resource Download

COA

Product Introduction

Bioactivity

Description	N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interactions and has potential anticancer activity for cancer research.
In vitro	N-deacetylated BMS-202 disrupts the interaction between PD-1 and PD-L1, potentially enhancing the immune response against various types of tumors. Using antibodies to target PD-L1 and block its binding with PD-1 has proven effective in reactivating and enhancing T cell activation across multiple systems [1].

Chemical Properties

Molecular Weight	377.48
Formula	C₂₃H₂₇N₃O₂
Cas No.	2310135-18-1
Smiles	N=1C(OCC2=CC=CC(C=3C=CC=CC3)=C2C)=CC=C(C1OC)CNCCN
Relative Density.	1.127 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (79.47 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.3 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6491 mL	13.2457 mL	26.4915 mL	132.4573 mL
5 mM	0.5298 mL	2.6491 mL	5.2983 mL	26.4915 mL
10 mM	0.2649 mL	1.3246 mL	2.6491 mL	13.2457 mL
20 mM	0.1325 mL	0.6623 mL	1.3246 mL	6.6229 mL
50 mM	0.0530 mL	0.2649 mL	0.5298 mL	2.6491 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc