Anti-ALDH1A1 Antibody (6M553)

Name: Anti-ALDH1A1 Antibody (6M553)
Brand: TargetMol
SKU: TMAY-01851
Rating: 4.5 (1 reviews)

(Synonyms: RALDH1, PUMB1, HEL-S-53e, HEL-9, HEL12, ALDH-E1, ALDH11, ALDH1, aldehyde dehydrogenase 1 family, member A1, ALDC) Copy Product Info

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Synonyms: RALDH1, PUMB1, HEL-S-53e, HEL-9, HEL12, ALDH-E1, ALDH11, ALDH1, aldehyde dehydrogenase 1 family, member A1, ALDC

Catalog No. TMAY-01851 Copy Product Info

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Anti-ALDH1A1 Antibody (6M553) is a Mouse antibody targeting ALDH1A1. Anti-ALDH1A1 Antibody (6M553) can be used in ELISA,FCM,ICC/IF,WB.

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$94	7-10 days	7-10 days
100 μL	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-ALDH1A1 Antibody (6M553) is a Mouse antibody targeting ALDH1A1. Anti-ALDH1A1 Antibody (6M553) can be used in ELISA,FCM,ICC/IF,WB.
Synonyms	RALDH1, PUMB1, HEL-S-53e, HEL-9, HEL12, ALDH-E1, ALDH11, ALDH1, aldehyde dehydrogenase 1 family, member A1, ALDC
Ig Type	Mouse IgG1
Clone	6M553
Reactivity	Human
Specificity	Human ALDH1A1 No cross-reactivity in ELISA with E.coli cell lysate

Application	ELISA FCM ICC/IF WB
Recommended Dose	WB: 1:500-1:2000; ELISA: 1:1000-1:2000; ICC-IF: 1:20-1:100; FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALDH1 (rh ALDH1; TMPY-01583; NP_000680.2; Ser 2-Ser 501). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography .
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. Increased ALDH1A1 activity has been found in the stem cell populations of leukemia and some solid tumors. In tumor specimens, increased ALDH1A1 immunopositivity was found not only in secretory type cancer epithelial cells but also in neuroendocrine tumor populations. ALDH1 has been identified as a reliable marker of breast cancer stem cells. ALDH1 expression in primary cancer is an independent prognostic factor in node-positive breast cancer patients. ALDH1A1 plays a key role in normal hematopoiesis, and as a TLX1 transcriptional target, ALDH1A1 may contribute to the ability of this homeoprotein to alter cell fate and induce tumor growth.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	FITC/PE
Antibody Types Available	3

Antigen Details

Immunogen	Recombinant Protein: Human ALDH1 protein (TMPY-01583)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.