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HKOH-1r

Name: HKOH-1r
Brand: TargetMol
SKU: T39600
Rating: 4.5 (1 reviews)

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HKOH-1r is a highly sensitive and selective fluorescent probe used for detecting endogenous hydroxyl radicals in living cells [1].

Cas No. 2138472-08-7

Pack Size	Price	USA Stock	Global Stock	Quantity
5 mg	$747	Inquiry	Inquiry
10 mg	$1,280	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:Orange

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COA

Product Introduction

Bioactivity

Description	HKOH-1r is a highly sensitive and selective fluorescent probe used for detecting endogenous hydroxyl radicals in living cells [1].
In vitro	HKOH-1r (0.1-50 μM; 24 h) shows negligible or no cytotoxicity in both RAW264.7 cells and Hela cells[1]. HKOH-1r (5 μM; 30 min) detects endogenous ? OH in the flow cytometry platform in RAW264.7 cells[1].

Chemical Properties

Molecular Weight	932.24
Formula	C₃₃H₂₁Cl₂I₂NO₁₁
Cas No.	2138472-08-7
Relative Density.	no data available

Storage & Solubility Information

Storage

Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 76 mg/mL (81.52 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0727 mL	5.3634 mL	10.7269 mL	53.6343 mL
5 mM	0.2145 mL	1.0727 mL	2.1454 mL	10.7269 mL
10 mM	0.1073 mL	0.5363 mL	1.0727 mL	5.3634 mL
20 mM	0.0536 mL	0.2682 mL	0.5363 mL	2.6817 mL
50 mM	0.0215 mL	0.1073 mL	0.2145 mL	1.0727 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc