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Anti-ACRV1 Antibody (4E707) is a Mouse antibody targeting ACRV1. Anti-ACRV1 Antibody (4E707) can be used in ELISA(Cap).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 20 μL | $68 | 7-10 days | 7-10 days | |
| 100 μL | $198 | 7-10 days | 7-10 days |
| Description | Anti-ACRV1 Antibody (4E707) is a Mouse antibody targeting ACRV1. Anti-ACRV1 Antibody (4E707) can be used in ELISA(Cap). |
| Synonyms | SPACA2, SP-10, D11S4365, acrosomal vesicle protein 1 |
| Ig Type | Mouse IgG1 |
| Clone | 4E707 |
| Reactivity | Human |
| Specificity | Human ACRV1 |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ACRV1 (rh ACRV1; TMPY-01813; P26436-1; Gln22-Ile265). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest transcript of ACRV1 / SP-1 is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. ACRV1 / SP-1 is a testis-specific acrosomal protein that has been detected in several species including humans. It may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. ACRV1 / SP-1 may be involved in sperm-zona binding or penetration. It is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ACRV1 Protein (TMPY-01813) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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