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Anti-CD200RLa Antibody-Biotin (5K764) (Synonyms: CD200RLa, CD200 receptor 1 like)

Catalog No. TMAY-01941B Copy Product Info
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Anti-CD200RLa Antibody-Biotin (5K764) is a Biotin-conjugated Mouse antibody targeting CD200RLa. Anti-CD200RLa Antibody-Biotin (5K764) can be used in ELISA.

Anti-CD200RLa Antibody-Biotin (5K764)

Copy Product Info
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Catalog No. TMAY-01941B
Synonyms CD200RLa, CD200 receptor 1 like

Anti-CD200RLa Antibody-Biotin (5K764) is a Biotin-conjugated Mouse antibody targeting CD200RLa. Anti-CD200RLa Antibody-Biotin (5K764) can be used in ELISA.

Anti-CD200RLa Antibody-Biotin
(5K764)
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$2947-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD200RLa Antibody-Biotin (5K764) is a Biotin-conjugated Mouse antibody targeting CD200RLa. Anti-CD200RLa Antibody-Biotin (5K764) can be used in ELISA.
SynonymsCD200RLa, CD200 receptor 1 like
Ig Type
Mouse IgG1
Clone
5K764
Reactivity
Human
Specificity
Human CD200RLa
Application
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD200RLa / CD200R1L (rh CD200RLa / CD200R1L; TMPY-01591; AAT00538.1; Met1-Leu239) and then biotinylated. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and then biotinylated.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCell surface glycoprotein CD2 receptor 2, also known as Cell surface glycoprotein CD2 receptor 1-like, Cell surface glycoprotein OX2 receptor 2, CD2 receptor-like 2, CD2Rla, CD2R1L and CD2R2, is a single-pass type I membrane protein which belongs to theCD2R family. CD2R1L / CD2R2. It contains oneIg-like C2-type (immunoglobulin-like) domain and oneIg-like V-type (immunoglobulin-like) domain. CD2 is a transmembrane protein delivering immunoregulatory signals after engagement of CD2R. A family of CD2Rs exist ( CD2R1, CD2R2, CD2R3, CD2R4 ) with different tissue expression and functional activity. In the presence of anti-CD2R2 / CD2R3 monoclonal antibodies (mAbs), bone-marrow cells cultured in the presence of (interleukin [IL]-4+granulocyte-macrophage colony-stimulating factor) differentiate into dendritic cells (DCs), which induce CD4+CD25+ Treg. Interaction between the relatively ubiquitously expressed molecule CD2 and one of its receptors, CD2R1, resulted in direct suppression of alloreactivity, engagement of alternate receptors led instead to altered differentiation of dendritic cells (DCs) from marrow precursors, which could in turn foster development of Foxp3(+) regulatory T cells. Unlike anti-CD2R1, anti-CD2R2 both promotes development of DCs with capacity to induce Treg and directly augments thymocyte production of Treg.
Related Conjugates and Formulations
Conjucates
Biotin
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Protein: Human CD200RLa / CD200R1L protein (TMPY-01591)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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