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Isoglobotriaose

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Catalog No. T82032Cas No. 41744-59-6
Alias Gala-3Galb-4Glc

Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].

Isoglobotriaose

Isoglobotriaose

😃Good
Catalog No. T82032Alias Gala-3Galb-4GlcCas No. 41744-59-6
Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].
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Product Introduction

Bioactivity
Description
Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].
In vitro
Isoglobotriaose is produced through a one-pot enzymatic synthesis involving lactose, glucose-1-phosphate (Glc-1-P), and uridine 5'-triphosphate (UTP). This reaction system employs three enzymes: UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and α1-3 galactosyltransferase (α1-3GalT)[1].
SynonymsGala-3Galb-4Glc
Chemical Properties
Molecular Weight504.44
FormulaC18H32O16
Cas No.41744-59-6
SmilesO([C@@H]1[C@@H](O)[C@H](O[C@@H]([C@@H]([C@H](C=O)O)O)[C@@H](CO)O)O[C@H](CO)[C@@H]1O)[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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