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Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].

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| Description | Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2]. |
| In vitro | Isoglobotriaose is produced through a one-pot enzymatic synthesis involving lactose, glucose-1-phosphate (Glc-1-P), and uridine 5'-triphosphate (UTP). This reaction system employs three enzymes: UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and α1-3 galactosyltransferase (α1-3GalT)[1]. |
| Synonyms | Gala-3Galb-4Glc |
| Molecular Weight | 504.44 |
| Formula | C18H32O16 |
| Cas No. | 41744-59-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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