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Benzyl benzoate

Name: Benzyl benzoate
Brand: TargetMol
SKU: T0729
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0729Cas No. 120-51-4

Alias Scabitox, Novoscabin, Benzoic acid benzyl ester, Ascabiol

Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (particularly at night), and may lead to a secondary infection. Benzyl benzoate is useful in the therapy of scabies because it is lethal to this mite. It is also used for the therapy of lice affection of the body and head. Benzyl benzoate is not the therapy of choice for scabies because of its irritant properties.

Benzyl benzoate

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Purity: 99.75%

Catalog No. T0729Alias Scabitox, Novoscabin, Benzoic acid benzyl ester, AscabiolCas No. 120-51-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$31	In Stock	In Stock
5 g	$48	-	In Stock
10 g	$58	-	In Stock
25 g	$79	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.75%

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (particularly at night), and may lead to a secondary infection. Benzyl benzoate is useful in the therapy of scabies because it is lethal to this mite. It is also used for the therapy of lice affection of the body and head. Benzyl benzoate is not the therapy of choice for scabies because of its irritant properties.
In vitro	Benzyl benzoate possess oestrogenic activity in MCF7 human breast cancer cells in vitro. It is able to increase the growth of oestrogen-dependent MCF7 human breast cancer cells[1].
Cell Research	Cells are added to the required volume of phenol red-free RPMI 1640 medium containing 5% DCFCS at a concentration of about 0.2 × 105 cells ml−1 and plated in monolayer in 0.5 ml aliquots into 24-well plastic tissue culture dishes (Nunc). After 24 h, the medium is changed to the same medium but containing the required concentration of test compound. Culture medium is changed routinely every 3–4 days. Cell counts are performed by counting released nuclei on a model ZBI Coulter Counter. (Only for Reference)
Synonyms	Scabitox, Novoscabin, Benzoic acid benzyl ester, Ascabiol

Chemical Properties

Molecular Weight	212.24
Formula	C₁₄H₁₂O₂
Cas No.	120-51-4
Smiles	O=C(OCc1ccccc1)c1ccccc1
Relative Density.	Ca. 1.112. Temperature:25 °C.

Storage & Solubility Information

Storage

keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 260 mg/mL (1225.03 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.42 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.7116 mL	23.5582 mL	47.1165 mL	235.5824 mL
5 mM	0.9423 mL	4.7116 mL	9.4233 mL	47.1165 mL
10 mM	0.4712 mL	2.3558 mL	4.7116 mL	23.5582 mL
20 mM	0.2356 mL	1.1779 mL	2.3558 mL	11.7791 mL
50 mM	0.0942 mL	0.4712 mL	0.9423 mL	4.7116 mL
100 mM	0.0471 mL	0.2356 mL	0.4712 mL	2.3558 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc